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Structure of 227197-72-0
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6-Chloro-1,3-benzoxazole is a bench-stable heterocyclic scaffold featuring a chlorine substituent at the 6-position, enhancing electrophilic reactivity. This electron-deficient aromatic system integrates readily into medicinal chemistry libraries and serves as a key building block for bioactive molecules. The fused oxazole ring imparts rigidity and metabolic stability, making it valuable in drug discovery and materials science applications.
6-Chloro-1,3-benzoxazole serves as a versatile heterocyclic building block in medicinal chemistry and materials science. Its chlorine substituent enables palladium-catalyzed cross-coupling reactions, facilitating the construction of biaryl and extended π-conjugated systems. The benzoxazole core exhibits good thermal stability, moderate polarity, and compatibility with diverse functional groups, enabling straightforward purification and integration into complex molecular architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: