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CS-W001157 4
Total: USD 88.00

4-(4-Methylpiperazin-1-yl)phenylboronic acid

  • CAS No. 229009-40-9

  • Cat. No. CS-W003780
  • Purity≥97%
  • MDL No.MFCD11223486
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-(4-Methylpiperazin-1-yl)phenylboronic acid|CS-W003780

Structure of 229009-40-9

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Description

4-(4-Methylpiperazin-1-yl)phenylboronic acid features a boronate moiety linked to a para-substituted phenyl ring bearing a sterically hindered, electron-rich piperazine. This structure enables efficient Suzuki-Miyaura coupling under standard conditions, delivering biaryl architectures with high functional group tolerance and excellent stability during storage and handling.

Application

4-(4-Methylpiperazin-1-yl)phenylboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. The boronic acid functionality exhibits good bench stability and compatibility with diverse functional groups, facilitating straightforward purification and integration into complex molecular architectures. Its piperazine-based side chain provides enhanced solubility and potential for downstream derivatization in medicinal chemistry campaigns.

General Information

  • CAS No. 229009-40-9
  • Cat. No. CS-W003780
  • Purity ≥97%
  • MDL No. MFCD11223486
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₇BN₂O₂
  • Molecular Weight 220.08
  • Synonym(s) Boronic acid, B-[4-(4-methyl-1-piperazinyl)phenyl]-
  • SMILES OB(c1ccc(cc1)N1CCN(CC1)C)O

Computational Chemistry Data

  • TPSA   46.94
  • LogP   -0.8818
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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