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Structure of 22942-87-6
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3-Bromoindolin-2-one is a brominated heterocyclic compound featuring a reactive ketone and a pendant bromide at the 3-position. This structure enables direct functionalization in cross-coupling reactions and facilitates incorporation into bioactive scaffolds. The molecule exhibits good stability under standard conditions and serves as a key intermediate in medicinal chemistry campaigns targeting kinase inhibitors and other pharmaceutical agents.
3-Bromoindolin-2-one serves as a versatile building block in medicinal chemistry, enabling efficient access to biologically relevant indole and isoindoline scaffolds. The bromine substituent facilitates palladium-catalyzed cross-coupling reactions, while the ketone functionality supports nucleophilic additions and enolate derivatization. Its stability under standard synthetic conditions and compatibility with diverse functional groups make it a practical choice for modular synthesis of drug candidates and heterocyclic libraries.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: