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Structure of 22952-24-5
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6-Nitrobenzo[d]isothiazol-3(2H)-one 1,1-dioxide is a potent, bench-stable heterocyclic electrophile featuring a strongly electron-deficient core. This compound integrates a nitro group at the para position relative to the isothiazolone ring, enhancing reactivity for conjugate addition and targeted protein labeling. The sulfone moiety ensures high stability under ambient conditions, enabling reliable use in chemical biology workflows.
6-Nitrobenzo[d]isothiazol-3(2H)-one 1,1-dioxide serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to bioactive scaffolds. Its electron-deficient core facilitates nucleophilic substitution reactions and exhibits favorable bench stability. The molecule's dual functional groups—nitro and sulfonamide—support orthogonal reactivity, aiding in the construction of complex molecular architectures through established coupling protocols.
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GHS Pictogram :
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GHS No : GHS07,GHS09
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Signal Word : Warning
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UN#: 3077
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Class : 9
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: