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Structure of 22958-64-1
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This sulfonamide-containing acetic acid derivative integrates a polar, electron-withdrawing sulfamoyl group with a flexible acetyl side chain. The para-substituted phenyl scaffold enhances solubility and metabolic stability, making it suitable for medicinal chemistry campaigns targeting kinase inhibition and protein-protein interactions.
2-(4-Sulfamoylphenyl)acetic acid serves as a versatile building block for sulfonamide-containing aromatic systems, enabling efficient access to biologically relevant scaffolds. Its carboxylic acid functionality facilitates direct amidation, esterification, or coupling reactions, while the para-sulfamoyl group offers enhanced solubility and metabolic stability. The molecule exhibits good bench stability and is readily purified by crystallization, making it well-suited for medicinal chemistry campaigns and API intermediate synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: