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Structure of 2304634-91-9
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tert-Butyl 3-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)azetidine-1-carboxylate features a boronate ester group enabling robust Suzuki-Miyaura coupling. The azetidine core imparts conformational rigidity, while the tert-butyl carbamate facilitates protection and orthogonal deprotection. This reagent streamlines access to complex pyrazole-containing scaffolds in medicinal chemistry.
tert-Butyl 3-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)azetidine-1-carboxylate serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The pyrazole-borane moiety enables efficient C–C bond formation under mild conditions, while the azetidine core provides a strained, bioactive scaffold relevant to medicinal chemistry. Bench-stable and readily purified, it functions as a key intermediate in constructing complex heterocyclic architectures with high functional group tolerance and predictable reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: