(3R,4R)-3-Fluoropiperidin-4-ol hydrochloride

Name: (3R,4R)-3-Fluoropiperidin-4-ol hydrochloride
Brand: ChemScene
Availability: InStock
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CAS No. 2306245-02-1
Cat. No. CS-0368740
Purity≥97%
MDL No.None

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Type	HazMat Fee
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FedEx Limited Quantities Ground	$0.00
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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(3R,4R)-3-Fluoropiperidin-4-ol hydrochloride|CS-0368740

Structure of 2306245-02-1

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Description

This chiral piperidine derivative features a fluorinated, hydroxylated core with defined stereochemistry at the 3- and 4-positions. The hydrochloride salt enhances solubility and stability for use in synthetic medicinal chemistry. It serves as a key building block for bioactive molecules requiring constrained amine functionality and polar handle integration.

Application

(3R,4R)-3-Fluoropiperidin-4-ol hydrochloride serves as a stereochemically defined building block for fluorinated piperidine scaffolds prevalent in medicinal chemistry. Its bench-stable hydrochloride salt facilitates handling and purification, while the 3-fluoro and 4-hydroxyl groups enable directed functionalization via nucleophilic substitution or oxidation reactions. This configuration supports predictable conformational control in target molecules, making it valuable for synthesizing bioactive compounds requiring defined stereochemistry and metabolic stability.

General Information

CAS No. 2306245-02-1
Cat. No. CS-0368740
Purity ≥97%
MDL No. None
Storage Store at room temperature, keep dry and cool
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₁₁ClFNO
Molecular Weight 155.60
Synonym(s) None
SMILES F[C@H]1[C@@H](CCNC1)O.Cl

Computational Chemistry Data

TPSA 32.26
LogP 0.1005
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 0

Safety Information

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GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Other Classifications

Building Blocks Functional Group Fluoride

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(3R,4R)-3-Fluoropiperidin-4-ol hydrochloride

CAS No. 2306245-02-1

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