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Structure of 23405-32-5
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Methyl 1-oxo-1,3-dihydroisobenzofuran-5-carboxylate is a bench-stable, electron-deficient heterocyclic ester featuring a fused benzene–γ-lactone core. This structural motif enables direct integration into transition-metal-catalyzed coupling reactions and serves as a key building block for complex natural product scaffolds.
Methyl 1-oxo-1,3-dihydroisobenzofuran-5-carboxylate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to functionalized benzofuran scaffolds. Its ortho-quinone methide precursor functionality facilitates [4+2] cycloadditions and nucleophilic additions under mild conditions. The ester group provides a handle for selective transformations, while the fused aromatic system offers stability and compatibility with standard reaction protocols. This compound functions reliably in multistep syntheses requiring controlled reactivity and predictable regiochemistry.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: