2-Bromo-6-iodopyridine

Name: 2-Bromo-6-iodopyridine
Brand: ChemScene
Availability: InStock
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CAS No. 234111-08-1
Cat. No. CS-W012247
Purity≥98%
MDL No.MFCD08059557

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

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Structure of 234111-08-1

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Description

2-Bromo-6-iodopyridine is a halogenated pyridine derivative featuring complementary reactive sites for cross-coupling transformations. The bromine and iodine substituents enable sequential functionalization under palladium catalysis, offering precise control in building complex heterocyclic architectures. This compound serves as a key intermediate in the synthesis of bioactive molecules and advanced materials.

Application

2-Bromo-6-iodopyridine serves as a versatile building block in cross-coupling chemistry, enabling efficient access to substituted pyridines via palladium-catalyzed reactions. The orthogonal halogen reactivity—bromine more reactive than iodine—facilitates sequential functionalization, while the molecule exhibits excellent bench stability and compatibility with standard reaction conditions. Its defined substitution pattern supports predictable regiochemistry in C–C and C–heteroatom bond formation, making it ideal for constructing complex heterocyclic scaffolds in medicinal chemistry and materials science.

General Information

CAS No. 234111-08-1
Cat. No. CS-W012247
Purity ≥98%
MDL No. MFCD08059557
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₃BrIN
Molecular Weight 283.89
Synonym(s) 6-BROMO-2-IODOPYRIDINE
SMILES IC1=CC=CC(Br)=N1

Computational Chemistry Data

TPSA 12.89
LogP 2.4487
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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2-Bromo-6-iodopyridine

CAS No. 234111-08-1

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