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CS-W001157 4
Total: USD 88.00

4-Iodostyrene,98% (stabilized with TBC)

  • CAS No. 2351-50-0

  • Cat. No. CS-0158021
  • Purity98% (stabilized with TBC)
  • MDL No.MFCD00045321

*For research and further manufacturing use only, not for direct human use.

4-Iodostyrene,98% (stabilized with TBC)|CS-0158021

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General Information

  • CAS No. 2351-50-0
  • Cat. No. CS-0158021
  • Purity 98% (stabilized with TBC)
  • MDL No. MFCD00045321
  • Storage -20°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇I
  • Molecular Weight 230.05
  • Synonym(s) KWHSBYQFELZKKS-UHFFFAOYSA-N
  • SMILES C=CC1=CC=C(C=C1)I

Description

4-Iodostyrene, stabilized with TBC, features a para-iodinated phenyl ring enabling efficient palladium-catalyzed cross-coupling reactions. This bench-stable derivative combines enhanced shelf life with predictable reactivity, facilitating seamless integration into synthetic workflows requiring halogen-functionalized aryl building blocks.

Application

4-Iodostyrene, 98% (stabilized with TBC) serves as a reliable building block in palladium-catalyzed cross-coupling reactions, enabling efficient C–C bond formation under standard Suzuki, Stille, and Negishi conditions. The terminal vinyl iodide functionality exhibits high reactivity and excellent functional group tolerance, while stabilization with TBC enhances shelf life and handling stability at ambient conditions. Ideal for synthesizing conjugated biaryls and advanced intermediates in pharmaceutical and materials chemistry workflows.

Synthesis

  • Route1

    References

    • Grirrane, Abdessamad; Garcia, Hermenegildo; Corma, Avelino Journal of Catalysis, 2013 , vol. 302, p. 49 - 57
  • Route2

    References

    • Partridge, Benjamin M.; Hartwig, John F. Organic Letters, 2013 , vol. 15, # 1 p. 140 - 143
  • Route3

    References

    • Tyson, Elizabeth L.; Ament, Michael S.; Yoon, Tehshik P. Journal of Organic Chemistry, 2013 , vol. 78, # 5 p. 2046 - 2050

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   2.9342
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   1

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