Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Decitabine

  • CAS No. 2353-33-5

  • Cat. No. CS-0372
  • Molecule weight228.21
  • Purity≥98%
  • MDL No.MFCD00043011

*For research and further manufacturing use only, not for direct human use.

Decitabine|CS-0372

Structure of 2353-33-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 2353-33-5
  • Cat. No. CS-0372
  • Purity ≥98%
  • MDL No. MFCD00043011
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₂N₄O₄
  • Molecular Weight 228.21
  • Synonym(s) 5-Aza-2'-deoxycytidine; 5-AZA-CdR; NSC 127716
  • SMILES O[C@H]1C[C@H](N2C(N=C(N)N=C2)=O)O[C@@H]1CO

Description

Inducing DNA hypomethylation through irreversible inhibition of DNMT1, 5-Aza-2′-deoxycytidine (CAS 2353-33-5) triggers transcriptional reactivation in silenced tumor suppressor loci, driving epigenetic reprogramming in myeloid malignancies.

Application

5-Aza-2′-deoxycytidine (CAS 2353-33-5) serves as a critical reference standard in USP-compliant assays, enabling precise quantification of decitabine purity and stability through chromatographic and spectroscopic validation. It ensures batch-to-batch consistency. This high-purity compound supports regulatory testing and method development in oncology research.

Synthesis

  • Route1

    References

    • EP2371825 A1, ; Page/Page column 9 ;
  • Route2

    References

    • EP2048151 A1, ; Page/Page column 3 ;
  • Route3
    • 5-Acetoxy-2-(((4-chlorobenzoyl)oxy)methyl)tetrahydrofuran-3-yl 4-chlorobenzoate|CS-0454126
      1207459-15-1
    • Bis(trimethylsilyl)-5-azacytosine|CS-0032923
      52523-35-0
    • ~%
    • In-stock
      Decitabine|CS-0372
      2353-33-5

    References

    • US2010/36112 A1, ; Page/Page column 7-8 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335-H341-H360
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   123.49
  • LogP   -2.1388
  • H_Acceptors   8
  • H_Donors   3
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • Decitabine sigmaDecitabine manufacturerDecitabine priceDecitabine structureDecitabine SDSbuy DecitabineDecitabine supplierDecitabine usesDecitabine molecular weightprice of DecitabineDecitabine chemical name formula of Decitabine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label