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Structure of 2353-33-5
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Inducing DNA hypomethylation through irreversible inhibition of DNMT1, 5-Aza-2′-deoxycytidine (CAS 2353-33-5) triggers transcriptional reactivation in silenced tumor suppressor loci, driving epigenetic reprogramming in myeloid malignancies.
5-Aza-2′-deoxycytidine (CAS 2353-33-5) serves as a critical reference standard in USP-compliant assays, enabling precise quantification of decitabine purity and stability through chromatographic and spectroscopic validation. It ensures batch-to-batch consistency. This high-purity compound supports regulatory testing and method development in oncology research.
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GHS Pictogram :
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GHS No : GHS07,GHS08
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335-H341-H360
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: