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Structure of 23530-40-7
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N-Methyl-2-nitrobenzenesulfonamide features a sulfonamide group flanked by an electron-deficient aromatic ring and a methyl substituent, enhancing stability and solubility in organic media. This configuration supports its role as a key intermediate in the synthesis of bioactive sulfonamide derivatives, particularly in medicinal chemistry applications requiring robust functional group tolerance under standard conditions.
N-Methyl-2-nitrobenzenesulfonamide serves as a stable, bench-ready sulfonamide building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-nitro group enables directed metalation and subsequent functionalization, while the N-methyl sulfonamide moiety offers enhanced solubility and metabolic stability. The compound facilitates efficient coupling reactions and acts as a versatile scaffold in medicinal chemistry campaigns targeting kinase inhibitors and antimicrobial agents.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: