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Structure of 23680-40-2
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Methyl 3-bromopropynoate is a reactive acetylenic ester featuring a bromine-substituted alkyne moiety. This compound integrates readily into cross-coupling and cycloaddition reactions, offering high functional group tolerance. The pendant ester group enables downstream derivatization, while the terminal alkyne facilitates efficient coupling under mild conditions.
Methyl 3-bromopropynoate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted alkynes and functionalized heterocycles. Its bromine-substituted alkyne moiety facilitates palladium-catalyzed coupling reactions, including Sonogashira and Stille couplings, with high functional group tolerance. The ester group provides compatibility with standard transformations, while the molecule exhibits good bench stability and ease of purification—key attributes for reliable use in medicinal chemistry and process development workflows.
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GHS No : GHS02,GHS05,GHS07
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Signal Word : Danger
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UN#: 2924
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Class : 3,8
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Packing Group : Ⅲ
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Hazard Statements : H225-H302-H315-H318
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P264-P270-P280-P302+P352-P330-P362+P364-P370+P378-P501
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Lot numbers can be found on the outside label of a product: