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Structure of 23688-89-3
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6-Chloropyrazine-2-carboxylic acid features a chlorine-substituted pyrazine core paired with a carboxylic acid group, enabling direct functionalization in heterocyclic synthesis. This electron-deficient scaffold integrates readily into pharmaceutical intermediates and agrochemical frameworks, offering enhanced reactivity under standard conditions.
6-Chloropyrazine-2-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the pyrazine core through palladium-catalyzed cross-coupling reactions. Its carboxylic acid group facilitates salt formation and derivatization, while the chlorine atom provides a reliable handle for nucleophilic substitution under mild conditions. The molecule exhibits good bench stability and compatibility with common protecting groups, making it suitable for modular synthesis of heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: