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Structure of 2369-18-8
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2-Fluoro-3-methylpyridine is a fluorinated heterocycle featuring a methyl group at the 3-position and a fluorine atom at the 2-position, offering enhanced electron-withdrawing character and improved metabolic stability. This scaffold integrates readily into pharmaceutical intermediates and agrochemicals, serving as a key building block for bioactive molecules.
2-Fluoro-3-methylpyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal reactivity profile. The fluorine and methyl groups provide distinct electronic and steric modulation, enhancing regioselectivity in C–H functionalization. Its bench-stable nature and compatibility with common protecting group strategies facilitate integration into multi-step syntheses of heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS02,GHS07
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H226-H315-H319-H335
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501
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Lot numbers can be found on the outside label of a product: