Cbz-Lys(Boc)-OH

Name: Cbz-Lys(Boc)-OH
Brand: ChemScene
Availability: InStock
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CAS No. 2389-60-8
Cat. No. CS-W009749
Purity≥98%
MDL No.MFCD00062271

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

Structure of 2389-60-8

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Description

Cbz-Lys(Boc)-OH is a protected lysine derivative featuring a carbobenzoxy (Cbz) group at the α-amino terminus and a tert-butoxycarbonyl (Boc) group on the side-chain amine. This dual protection enables selective deprotection strategies in peptide synthesis, allowing sequential manipulation of functional groups under standard conditions. The molecule exhibits enhanced stability during handling and storage, facilitating reliable incorporation into complex peptide architectures.

Application

Cbz-Lys(Boc)-OH serves as a key amino acid building block for peptide synthesis, offering orthogonal protection of both the α-amino and ε-amino groups. The Cbz group enables mild removal via hydrogenolysis, while the Boc moiety is readily cleaved with trifluoroacetic acid. This dual protection strategy facilitates efficient sequential coupling in solid-phase and solution-phase peptide assembly, with excellent bench stability and straightforward purification.

General Information

CAS No. 2389-60-8
Cat. No. CS-W009749
Purity ≥98%
MDL No. MFCD00062271
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₉H₂₈N₂O₆
Molecular Weight 380.44
Synonym(s) None
SMILES O=C(O)[C@H](CCCCNC(OC(C)(C)C)=O)NC(OCC1=CC=CC=C1)=O

Computational Chemistry Data

TPSA 113.96
LogP 3.061
H_Acceptors 5
H_Donors 3
Rotatable_Bonds 9

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Life Science Amino Acids and their Derivatives Lysine and derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids N-Protected Amino Acids

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Cbz-Lys(Boc)-OH

CAS No. 2389-60-8

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