Mesitylhydrazine hydrochloride

Name: Mesitylhydrazine hydrochloride
Brand: ChemScene
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CAS No. 24006-09-5
Cat. No. CS-W022770
Purity≥95%
MDL No.MFCD00052268

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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Mesitylhydrazine hydrochloride|CS-W022770

Structure of 24006-09-5

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General Information

CAS No. 24006-09-5
Cat. No. CS-W022770
Purity ≥95%
MDL No. MFCD00052268
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₁₅ClN₂
Molecular Weight 186.68
Synonym(s) 1-Mesitylhydrazine hydrochloride
SMILES NNC1=C(C)C=C(C)C=C1C.[H]Cl

Description

Mesitylhydrazine hydrochloride offers a stable, moisture-tolerant platform for constructing hydrazone-based architectures. The electron-rich mesityl moiety enhances reactivity in condensation processes, while the hydrochloride salt form ensures ease of handling and solubility in polar solvents. This compound integrates seamlessly into synthetic workflows requiring robust hydrazine equivalents.

Application

Mesitylhydrazine hydrochloride serves as a stable, bench-friendly reagent for the synthesis of hydrazone derivatives and heterocyclic scaffolds. Its ortho-methyl substituents enhance electrophilic reactivity while improving crystallinity and ease of purification. Widely used in medicinal chemistry, it facilitates efficient access to triazoles, pyrazoles, and other nitrogen-rich frameworks via standard coupling and cyclization protocols.

Synthesis

Route1
- 88-05-1
- ~53%
- In-stock
  
  24006-09-5
References
- THE REGENTS OF THE UNIVERSITY OF CALIFORNIA Patent: WO2007/124494 A2, 2007 ; Location in patent: Page/Page column 54-55 ;

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS06
Signal Word : Danger	UN#: 2811
Class : 6.1	Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

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Computational Chemistry Data

TPSA 38.05
LogP 2.31926
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

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Mesitylhydrazine hydrochloride

CAS No. 24006-09-5

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