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CS-W001157 4
Total: USD 88.00

4-(Hydroxymethyl)piperidin-4-ol hydrochloride

  • CAS No. 240401-25-6

  • Cat. No. CS-0051144
  • Purity≥97%
  • MDL No.MFCD11845427

*For research and further manufacturing use only, not for direct human use.

4-(Hydroxymethyl)piperidin-4-ol hydrochloride|CS-0051144

Structure of 240401-25-6

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General Information

  • CAS No. 240401-25-6
  • Cat. No. CS-0051144
  • Purity ≥97%
  • MDL No. MFCD11845427
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₄ClNO₂
  • Molecular Weight 167.63
  • Synonym(s) 4-Hydroxy-4-hydroxyMethylpiperidine hydrochloride
  • SMILES OCC1(CCNCC1)O.Cl

Description

This hydrochloride salt features a piperidin-4-ol core with a hydroxymethyl substituent, delivering enhanced solubility and stability under standard conditions. The pendant hydroxyl group enables facile derivatization, while the protonated nitrogen ensures excellent handling in aqueous reaction systems.

Application

4-(Hydroxymethyl)piperidin-4-ol hydrochloride serves as a versatile bifunctional building block, enabling efficient access to piperidine-based scaffolds through standard functional group interconversions. The pendant hydroxymethyl and hydroxyl groups provide orthogonal handles for derivatization, while the hydrochloride salt ensures excellent bench stability and ease of handling. This compound facilitates rapid diversification in medicinal chemistry campaigns, particularly for targeted modifications in kinase inhibitors and CNS-directed therapeutics.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   52.49
  • LogP   -0.485
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

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