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Methyl 2,3-dihydroxybenzoate

  • CAS No. 2411-83-8

  • Cat. No. CS-0150887
  • Purity≥98%
  • MDL No.MFCD00039520

*For research and further manufacturing use only, not for direct human use.

Methyl 2,3-dihydroxybenzoate|CS-0150887

Structure of 2411-83-8

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General Information

  • CAS No. 2411-83-8
  • Cat. No. CS-0150887
  • Purity ≥98%
  • MDL No. MFCD00039520
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈O₄
  • Molecular Weight 168.15
  • Synonym(s) 2,3-Dihydroxybenzoic Acid Methyl Ester
  • SMILES COC(=O)C1=C(C(=CC=C1)O)O

Description

Methyl 2,3-dihydroxybenzoate features two adjacent hydroxyl groups on the aromatic ring, enhancing solubility and reactivity in synthetic transformations. This ortho-dihydroxy motif enables efficient coordination in metal-catalyzed couplings and serves as a key scaffold for bioactive molecule synthesis.

Application

Methyl 2,3-dihydroxybenzoate serves as a versatile dihydroxybenzoate building block in synthetic organic chemistry, enabling the construction of complex heterocyclic scaffolds and natural product analogs. Its ortho-dihydroxy functionality facilitates metal-catalyzed coupling reactions and oxidative transformations, while the methyl ester group provides compatibility with standard functional group interconversions. Bench-stable and readily purified by recrystallization, it functions effectively in multi-step syntheses requiring regioselective derivatization.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   66.76
  • LogP   0.8844
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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