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Structure of 2412578-71-1
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(S,R)-5-CF3-Pyox-In is a chiral pyridine-derived oxazoline featuring a trifluoromethyl group at the 5-position, offering enhanced electron-withdrawing character and improved metabolic stability. This scaffold integrates readily into asymmetric catalysis and ligand design, enabling efficient stereocontrol in transition-metal-catalyzed transformations under ambient conditions.
(S,R)-5-CF₃-Pyox-In serves as a versatile chiral building block for the synthesis of fluorinated heterocycles and bioactive scaffolds. Its trifluoromethylated pyrrolidine core exhibits enhanced metabolic stability and membrane permeability, enabling efficient incorporation into medicinal chemistry programs. The stereochemically defined framework facilitates predictable reactivity in coupling and cyclization processes, with excellent bench stability and compatibility with standard purification methods.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: