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Structure of 24195-03-7
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4-(Methoxycarbonyl)picolinic acid is a bench-stable, electron-deficient heterocyclic carboxylic acid featuring a strategically positioned methoxycarbonyl group at the C4 position of the pyridine ring. This functionalization enhances reactivity in coupling reactions and facilitates incorporation into bioconjugates, peptidomimetics, and polymer architectures. The molecule's polar ester moiety improves solubility in common organic solvents while maintaining compatibility with standard synthetic protocols.
4-(Methoxycarbonyl)picolinic acid serves as a versatile building block in medicinal chemistry and synthetic organic chemistry, enabling efficient access to pyridine-based scaffolds. Its ortho-carboxylate functionality facilitates direct amidation, esterification, and cyclization reactions, while the methoxycarbonyl group offers excellent stability and ease of purification. This compound functions as a key intermediate in the synthesis of heterocyclic compounds and bioactive molecules, particularly those requiring regiocontrolled substitution on a picolinate core.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: