Propane-1-sulfonamide

Name: Propane-1-sulfonamide
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 24243-71-8
Cat. No. CS-W022937
Purity≥97%
MDL No.MFCD03550611

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 24243-71-8

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General Information

CAS No. 24243-71-8
Cat. No. CS-W022937
Purity ≥97%
MDL No. MFCD03550611
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₃H₉NO₂S
Molecular Weight 123.17
Synonym(s) PROPANE-1-SULPHONAMIDE
SMILES CCCS(=O)(N)=O

Description

Propane-1-sulfonamide is a bench-stable, moisture-tolerant sulfonamide reagent featuring a primary amine functionality. This compound integrates readily into functionalized molecular architectures, serving as a reliable anchor point for conjugation and derivatization in synthetic organic chemistry and chemical biology applications.

Application

Propane-1-sulfonamide serves as a stable, bench-ready sulfonamide building block for medicinal chemistry and catalytic process development. Its well-defined reactivity enables straightforward incorporation into diverse heterocyclic scaffolds and peptide conjugates. The molecule exhibits excellent functional group tolerance, facilitates efficient purification via crystallization or chromatography, and functions reliably in standard coupling and derivatization protocols.

Synthesis

Route1
- 10147-36-1
- ~97%
- In-stock
  
  24243-71-8
References
- LABORATOIRES SERONO SA Patent: WO2008/101979 A1, 2008 ; Location in patent: Page/Page column 87 ;
Route2
- In-stock
  
  1120-71-4
- ~5%
- In-stock
  
  24243-71-8
References
- Smith, Michael B.; Wolinsky, Joseph Journal of Organic Chemistry, 1981 , vol. 46, p. 101 - 106

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 60.16
LogP -0.3151
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Sulfonamide

Key Words

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Propane-1-sulfonamide

CAS No. 24243-71-8

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