H-Phe(4-I)-OH

Name: H-Phe(4-I)-OH
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CAS No. 24250-85-9
Cat. No. CS-W007615
Molecule weight291.09
Purity≥96%
MDL No.MFCD00002602

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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General Information

CAS No. 24250-85-9
Cat. No. CS-W007615
Purity ≥96%
MDL No. MFCD00002602
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₁₀INO₂
Molecular Weight 291.09
Synonym(s) 4-Iodo-L-Phenylalanine
SMILES [C@H](N)(CC1=CC=C(I)C=C1)C(=O)O

Description

Intercalating into ribosomal translation machinery via UGA suppression, 4-Iodo-L-phenylalanine (CAS 24250-85-9) enables site-specific incorporation of iodinated residues into recombinant proteins for structural probing.

Application

4-Iodo-L-phenylalanine (CAS 24250-85-9) enables precise metabolic pathway tracing through its iodine-labeled aromatic ring, allowing researchers to monitor amino acid fate via spectrometric detection. This halogenated analog mimics phenylalanine yet alters reactivity. Its iodine facilitates electrophilic substitution and enhances molecular tracking in enzyme kinetics. Scientists use it to probe substrate specificity and engineer enzyme mimetics. The compound’s radiopaque nature supports imaging applications, while its integration into peptides aids protein folding studies and drug design.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 63.32
LogP 1.2456
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 3

Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Phenylalanine and derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Unnatural Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Unnatural Amino Acid Derivatives

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids non-Proteinogenic Amino Acids

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H-Phe(4-I)-OH

CAS No. 24250-85-9

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