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Structure of 243448-15-9
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This trifluorophenyl ketone features a sterically accessible carbonyl group flanked by electron-deficient aromatic substituents, enabling efficient coupling in transition-metal-catalyzed cross-coupling reactions. The bench-stable scaffold integrates readily into complex molecular architectures under standard conditions.
1-(2,3,4-Trifluorophenyl)ethan-1-one serves as a versatile building block in medicinal chemistry, enabling efficient construction of biologically relevant scaffolds. Its trifluorophenyl moiety imparts enhanced metabolic stability and lipophilicity, while the ketone group facilitates nucleophilic additions, reductive aminations, and coupling reactions. Bench-stable and readily purified by crystallization, it functions reliably in standard synthetic workflows for API intermediates and heterocycle synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: