2,4,6-Trichlorobenzaldehyde

Name: 2,4,6-Trichlorobenzaldehyde
Brand: ChemScene
Availability: InStock
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CAS No. 24473-00-5
Cat. No. CS-W018721
Purity≥97%
MDL No.MFCD12024961

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 24473-00-5

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Description

2,4,6-Trichlorobenzaldehyde features a highly electron-deficient aromatic ring stabilized by three chlorine substituents, enabling efficient electrophilic coupling reactions. This bench-stable aldehyde integrates readily into synthetic sequences requiring strong inductive withdrawal, particularly in pharmaceutical intermediates and heterocyclic scaffold construction.

Application

2,4,6-Trichlorobenzaldehyde serves as a highly functionalized aromatic aldehyde enabling efficient access to substituted heterocycles and pharmaceutical intermediates. Its electron-deficient aryl ring enhances reactivity in nucleophilic addition and condensation reactions, while the three chlorine substituents provide orthogonal handles for further derivatization. Bench-stable and readily purified by recrystallization, it functions reliably in standard synthetic workflows including Ugi, Mannich, and Stetter reactions.

General Information

CAS No. 24473-00-5
Cat. No. CS-W018721
Purity ≥97%
MDL No. MFCD12024961
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₃Cl₃O
Molecular Weight 209.46
Synonym(s) ghl.PD_Mitscher_leg0.543
SMILES ClC1=CC(Cl)=C(C=O)C(Cl)=C1

Computational Chemistry Data

TPSA 17.07
LogP 3.4593
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Aldehyde

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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2,4,6-Trichlorobenzaldehyde

CAS No. 24473-00-5

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