(S)-4-Isopropyloxazolidine-2,5-dione

Name: (S)-4-Isopropyloxazolidine-2,5-dione
Brand: ChemScene
Availability: InStock
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CAS No. 24601-74-9
Cat. No. CS-0101223
Purity≥97%
MDL No.MFCD03411320

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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(S)-4-Isopropyloxazolidine-2,5-dione|CS-0101223

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Description

(S)-4-Isopropyloxazolidine-2,5-dione is a chiral synthon featuring a rigid oxazolidinone core that enables stereoselective transformations. This bench-stable derivative integrates seamlessly into asymmetric synthesis workflows, where its defined stereochemistry directs enantioselective bond formation. The isopropyl substituent enhances solubility and modulates reactivity, facilitating efficient coupling reactions under mild conditions.

Application

(S)-4-Isopropyloxazolidine-2,5-dione serves as a chiral synthon for asymmetric synthesis, enabling stereoselective construction of β-amino acid derivatives and peptidomimetics. Its oxazolidinone core exhibits high bench stability, excellent functional group tolerance, and compatibility with standard coupling conditions. The molecule facilitates efficient enantioselective transformations via controlled ring-opening reactions, making it a practical building block for medicinal chemistry campaigns requiring defined stereochemistry.

General Information

CAS No. 24601-74-9
Cat. No. CS-0101223
Purity ≥97%
MDL No. MFCD03411320
Storage -20°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₉NO₃
Molecular Weight 143.14
Synonym(s) L-Valine N-carboxyanhydride
SMILES O=C(OC1=O)N[C@H]1C(C)C

Computational Chemistry Data

TPSA 55.4
LogP 0.2774
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(S)-4-Isopropyloxazolidine-2,5-dione

CAS No. 24601-74-9

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