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Structure of 24638-31-1
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3H-Imidazo[4,5-b]pyridine-6-carboxylic acid is a heterocyclic scaffold featuring a fused imidazopyridine core with a carboxylic acid group at the 6-position. This configuration imparts strong hydrogen-bonding capacity and enhanced solubility in polar media, enabling efficient incorporation into bioactive molecules. The electron-deficient ring system supports diverse synthetic transformations, including coupling reactions and derivatization under mild conditions.
3H-Imidazo[4,5-b]pyridine-6-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its fused imidazopyridine core exhibits enhanced metabolic stability and favorable pharmacokinetic properties, making it a valuable scaffold in drug discovery. The carboxylic acid functionality enables direct coupling reactions, derivatization, or salt formation, facilitating purification and solubility optimization. Bench-stable and compatible with standard synthetic protocols, it functions effectively in peptide coupling, amide bond formation, and transition-metal-catalyzed transformations.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: