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3H-Imidazo[4,5-b]pyridine-6-carboxylic acid

  • CAS No. 24638-31-1

  • Cat. No. CS-0043855
  • Purity≥97%
  • MDL No.None
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3H-Imidazo[4,5-b]pyridine-6-carboxylic acid|CS-0043855

Structure of 24638-31-1

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Description

3H-Imidazo[4,5-b]pyridine-6-carboxylic acid is a heterocyclic scaffold featuring a fused imidazopyridine core with a carboxylic acid group at the 6-position. This configuration imparts strong hydrogen-bonding capacity and enhanced solubility in polar media, enabling efficient incorporation into bioactive molecules. The electron-deficient ring system supports diverse synthetic transformations, including coupling reactions and derivatization under mild conditions.

Application

3H-Imidazo[4,5-b]pyridine-6-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its fused imidazopyridine core exhibits enhanced metabolic stability and favorable pharmacokinetic properties, making it a valuable scaffold in drug discovery. The carboxylic acid functionality enables direct coupling reactions, derivatization, or salt formation, facilitating purification and solubility optimization. Bench-stable and compatible with standard synthetic protocols, it functions effectively in peptide coupling, amide bond formation, and transition-metal-catalyzed transformations.

General Information

  • CAS No. 24638-31-1
  • Cat. No. CS-0043855
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅N₃O₂
  • Molecular Weight 163.13
  • Synonym(s) 1H-Imidazo[4,5-b]pyridine-6-carboxylic acid
  • SMILES OC(=O)C1=CC2=C(NC=N2)N=C1

Computational Chemistry Data

  • TPSA   78.87
  • LogP   0.6561
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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