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CS-W001157 4
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3,4-Dichloro-5-methyl-1H-pyrrole-2-carboxylic acid

  • CAS No. 24691-30-3

  • Cat. No. CS-0113021
  • Purity≥95%
  • MDL No.MFCD09991685
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3,4-Dichloro-5-methyl-1H-pyrrole-2-carboxylic acid|CS-0113021

Structure of 24691-30-3

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Description

This pyrrole carboxylic acid features a sterically hindered, electron-deficient core with dual chlorine substituents at the 3,4-positions and a methyl group at the 5-position. The carboxylic acid functionality enables direct coupling in peptide synthesis or derivatization workflows. Bench-stable under standard conditions, it integrates readily into complex heterocyclic architectures.

Application

3,4-Dichloro-5-methyl-1H-pyrrole-2-carboxylic acid serves as a versatile building block for heterocyclic synthesis, offering defined substitution patterns ideal for medicinal chemistry and agrochemical development. The carboxylic acid functionality enables direct coupling reactions, while the dichloro and methyl groups provide orthogonal reactivity and metabolic stability. Its bench-stable nature and compatibility with standard peptide coupling protocols facilitate efficient incorporation into complex molecular architectures.

General Information

  • CAS No. 24691-30-3
  • Cat. No. CS-0113021
  • Purity ≥95%
  • MDL No. MFCD09991685
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅Cl₂NO₂
  • Molecular Weight 194.02
  • Synonym(s) 3,4-dichloro-5-methyl-1H-Pyrrole-2-carboxylicacid
  • SMILES CC1=C(Cl)C(Cl)=C(C(O)=O)N1

Computational Chemistry Data

  • TPSA   53.09
  • LogP   2.32812
  • H_Acceptors   1
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group :
Hazard Statements : H301-H311-H331
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P405-P501

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