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Structure of 247564-73-4
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This trifluorophenylboronic acid features a highly electron-deficient aromatic ring that enhances its reactivity in Suzuki-Miyaura cross-coupling reactions. The ortho- and para-fluorine substituents stabilize the boronate moiety under standard conditions while improving solubility in polar aprotic solvents.
(2,3,5-Trifluorophenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation with aryl and heteroaryl halides. The trifluorophenyl group imparts enhanced metabolic stability and modulates electronic properties, making it valuable for constructing bioactive scaffolds. Its bench-stable nature and compatibility with diverse reaction conditions facilitate straightforward purification and integration into complex synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: