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Structure of 2476-35-9
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5-Bromo-2-methoxybenzoic acid features a bromine substituent at the 5-position and a methoxy group at the 2-position, creating a sterically constrained, electron-rich aromatic core. This configuration enhances its utility in cross-coupling reactions and as a building block for bioactive heterocycles. The carboxylic acid moiety enables direct derivatization or salt formation for improved solubility and handling under standard conditions.
5-Bromo-2-methoxybenzoic acid serves as a versatile building block in medicinal chemistry and materials science, enabling efficient diversification via Suzuki-Miyaura and Stille coupling reactions. Its bromo group provides a reliable handle for cross-coupling, while the methoxy and carboxylic acid functionalities offer orthogonal reactivity for derivatization. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for scalable synthesis and downstream functionalization in API development.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: