Boc-Orn(Z)-OH

Name: Boc-Orn(Z)-OH
Brand: ChemScene
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CAS No. 2480-93-5
Cat. No. CS-W011808
Purity≥97%
MDL No.MFCD00038259

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 2480-93-5

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Description

Boc-Orn(Z)-OH is a protected ornithine derivative featuring a benzylidene imine (Z) isomer and a tert-butoxycarbonyl group. This configuration enables selective incorporation into peptide chains under mild deprotection conditions, offering enhanced stability during synthesis workflows. The Z-configuration ensures defined stereochemistry at the side chain, critical for maintaining structural fidelity in complex peptide architectures.

Application

Boc-Orn(Z)-OH serves as a key building block in peptide synthesis, enabling the selective introduction of protected ornithine residues. The Boc group provides robust protection of the α-amino function, while the Z (benzyloxycarbonyl) moiety safeguards the side-chain amine. This dual protection facilitates orthogonal deprotection strategies and supports efficient coupling in solid-phase and solution-phase syntheses. The compound exhibits excellent bench stability and is compatible with standard activation protocols, making it a reliable choice for constructing bioactive peptides and heterocyclic scaffolds.

General Information

CAS No. 2480-93-5
Cat. No. CS-W011808
Purity ≥97%
MDL No. MFCD00038259
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₈H₂₆N₂O₆
Molecular Weight 366.41
Synonym(s) Nα-Boc-Nδ-Cbz-L-ornithine
SMILES O=C(O)[C@H](CCCNC(OCC1=CC=CC=C1)=O)NC(OC(C)(C)C)=O

Computational Chemistry Data

TPSA 113.96
LogP 2.6709
H_Acceptors 5
H_Donors 3
Rotatable_Bonds 8

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Boc-Orn(Z)-OH

CAS No. 2480-93-5

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