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CS-W001157 4
Total: USD 88.00

4-Hydroxyhippuric acid

  • CAS No. 2482-25-9

  • Cat. No. CS-0062311
  • Molecule weight195.17
  • Purity≥98%
  • MDL No.MFCD00237117

*For research and further manufacturing use only, not for direct human use.

4-Hydroxyhippuric acid|CS-0062311

Structure of 2482-25-9

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General Information

  • CAS No. 2482-25-9
  • Cat. No. CS-0062311
  • Purity ≥98%
  • MDL No. MFCD00237117
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉NO₄
  • Molecular Weight 195.17
  • Synonym(s) None
  • SMILES O=C(C1=CC=C(O)C=C1)NCC(O)=O

Description

4-Hydroxyhippuric acid features a hydroxyl group at the para position of the aromatic ring, enhancing solubility and reactivity in synthetic transformations. This derivative integrates readily into bioactive scaffolds and serves as a key intermediate in metabolite synthesis and pharmaceutical development under standard conditions.

Application

4-Hydroxyhippuric acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and peptide conjugates. Its dual functionality—carboxylic acid and phenolic hydroxyl—supports orthogonal derivatization, while its bench-stable nature facilitates straightforward purification and integration into standard coupling protocols.

Synthesis

  • Route1
    • 4-Hydroxybenzoic acid  Cetirizine Impurity|CS-0167040
      99-96-7
    • ~%
    • In-stock
      4-Hydroxyhippuric acid|CS-0062311
      2482-25-9

    References

    • Fischer,E. Chemische Berichte, 1908 , vol. 41, p. 2872 Chem. Zentralbl., 1908 , vol. 79, # II p. 314
  • Route2
    • p-Anisic acid, ≥99%|CS-1268349
      100-09-4
    • ~%
    • In-stock
      4-Hydroxyhippuric acid|CS-0062311
      2482-25-9

    References

    • Matsumura, Eiko; Shin, Takashi; Murao, Sawao; Kawano, Tatsu Agricultural and Biological Chemistry, 1985 , vol. 49, # 4 p. 973 - 980
  • Route3
    • null|null
      2078-13-9
    • ~%
    • In-stock
      4-Hydroxyhippuric acid|CS-0062311
      2482-25-9

    References

    • Schwarz, Gerd; Alberts, Heinrich; Kricheldorf, Hans R. Liebigs Annalen der Chemie, 1981 , # 7 p. 1257 - 1270

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   86.63
  • LogP   0.2066
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   3

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