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CS-W001157 4
Total: USD 88.00

Methyl 2-nitroacetate

  • CAS No. 2483-57-0

  • Cat. No. CS-0130670
  • Purity≥97%
  • MDL No.MFCD00075480
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Methyl 2-nitroacetate|CS-0130670

Structure of 2483-57-0

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Description

Methyl nitroacetate may be used:in the preparation of aromatic and heteroaromatic linear (E)--nitro-arylpentenoatesto generate phenyliodonium ylide, used in the highly enantioselective and diastereoselective Cu(I)-catalyzed cyclopropanation of alkenesin the preparation of methyl (Z)-2-nitro-3-(4-nitrophenyl)-2-propenoate, via reaction with 4-nitrobenzylideneaniline

Application

Methyl 2-nitroacetate serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of nitro-containing heterocycles and α-functionalized carboxylates. Its electrophilic α-carbon facilitates nucleophilic additions and condensations, particularly in the synthesis of pyrroles, isoxazoles, and β-nitro carbonyl compounds. The molecule exhibits good bench stability, mild handling requirements, and compatibility with diverse reaction conditions, making it a practical choice for multi-step syntheses and medicinal chemistry applications.

General Information

  • CAS No. 2483-57-0
  • Cat. No. CS-0130670
  • Purity ≥97%
  • MDL No. MFCD00075480
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₅NO₄
  • Molecular Weight 119.08
  • Synonym(s) Nitroacetic Acid Methyl Ester
  • SMILES O=C(OC)C[N+]([O-])=O

Computational Chemistry Data

  • TPSA   69.44
  • LogP   -0.5639
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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