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Structure of 2488-50-8
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5-(Fluorosulfonyl)-2-methoxybenzoic acid features a strategically positioned fluorosulfonyl group that imparts high electrophilicity, enabling efficient derivatization in synthetic transformations. The para-methoxy substituent enhances solubility and modulates electronic properties, while the carboxylic acid functionality provides a reliable anchor for coupling reactions. This compound serves as a robust building block for bioconjugation and medicinal chemistry applications.
5-(Fluorosulfonyl)-2-methoxybenzoic acid serves as a versatile building block for sulfonamide and sulfonyl fluoride incorporation in medicinal chemistry. Its fluorosulfonyl group enables direct functionalization under mild conditions, while the methoxy and carboxylic acid functionalities provide orthogonal handles for derivatization. The compound exhibits excellent bench stability and facilitates efficient purification via crystallization or standard chromatography, making it well-suited for use in multi-step synthesis of bioactive heterocycles and API intermediates.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: