Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1,5-Dibromo-2,4-dimethoxybenzene

  • CAS No. 24988-36-1

  • Cat. No. CS-0150486
  • Purity≥96%
  • MDL No.MFCD00061097

*For research and further manufacturing use only, not for direct human use.

1,5-Dibromo-2,4-dimethoxybenzene|CS-0150486

Structure of 24988-36-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 24988-36-1
  • Cat. No. CS-0150486
  • Purity ≥96%
  • MDL No. MFCD00061097
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈Br₂O₂
  • Molecular Weight 295.96
  • Synonym(s) 1,3-Dibromo-4,6-Dimethoxybenzene
  • SMILES COC1=CC(=C(C=C1Br)Br)OC

Description

1,5-Dibromo-2,4-dimethoxybenzene features two bromine atoms at electron-rich positions flanked by methoxy groups, enabling efficient coupling in cross-coupling reactions. The ortho-methoxy substituents enhance solubility and stabilize the aromatic core under standard conditions. This configuration supports reliable functionalization in synthetic sequences requiring selective halogenation.

Application

1,5-Dibromo-2,4-dimethoxybenzene serves as a versatile building block for palladium-catalyzed cross-coupling reactions, enabling efficient construction of substituted biaryls and heterocycles. The dimethoxy groups enhance solubility and stabilize the aromatic core, while the bromo substituents provide high reactivity in standard coupling protocols. Bench-stable and readily purified by flash chromatography, it facilitates reproducible synthesis of complex scaffolds in medicinal chemistry and materials science applications.

Synthesis

  • Route1

    References

    • Yang, Lujuan; Lu, Zhan; Stahl, Shannon S. Chemical Communications, 2009 , # 42 p. 6460 - 6462
  • Route2

    References

    • Peng, Xuefeng; Shao, Xiang-Feng; Liu, Zhong-Quan Tetrahedron Letters, 2013 , vol. 54, # 24 p. 3079 - 3081
  • Route3

    References

    • Bovicelli; Mincione; Antonioletti; Bernini; Colombari Synthetic Communications, 2001 , vol. 31, # 19 p. 2955 - 2963

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   18.46
  • LogP   3.2288
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1,5-Dibromo-2,4-dimethoxybenzene sigma1,5-Dibromo-2,4-dimethoxybenzene manufacturer1,5-Dibromo-2,4-dimethoxybenzene price1,5-Dibromo-2,4-dimethoxybenzene structure1,5-Dibromo-2,4-dimethoxybenzene SDSbuy 1,5-Dibromo-2,4-dimethoxybenzene1,5-Dibromo-2,4-dimethoxybenzene supplier1,5-Dibromo-2,4-dimethoxybenzene uses1,5-Dibromo-2,4-dimethoxybenzene molecular weightprice of 1,5-Dibromo-2,4-dimethoxybenzene1,5-Dibromo-2,4-dimethoxybenzene chemical name formula of 1,5-Dibromo-2,4-dimethoxybenzene
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label