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4-Oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxylic acid hydrochloride

  • CAS No. 2499661-06-0

  • Cat. No. CS-0169595
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxylic acid hydrochloride|CS-0169595

Structure of 2499661-06-0

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General Information

  • CAS No. 2499661-06-0
  • Cat. No. CS-0169595
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₇ClN₂O₃
  • Molecular Weight 226.62
  • Synonym(s) None
  • SMILES O=C1C=C(C(O)=O)N=C2C=CC=CN21.Cl

Description

This hydrochloride salt features a fused pyridopyrimidine core with a ketone and carboxylic acid at the 4- and 2-positions, enabling integration into bioactive scaffolds. The protonated form enhances solubility and stability under standard conditions, facilitating use in medicinal chemistry workflows.

Application

4-Oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxylic acid hydrochloride serves as a versatile building block for heterocyclic synthesis, enabling efficient access to fused pyridopyrimidine scaffolds. Its carboxylic acid functionality facilitates direct derivatization and coupling reactions, while the oxo and pyridine moieties provide enhanced solubility and stability under standard reaction conditions. The hydrochloride salt form improves handling and storage reliability, making it well-suited for medicinal chemistry campaigns and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   71.67
  • LogP   0.8145
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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