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Structure of 25095-57-2
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6,7-Dichloro-3,4-dihydronaphthalen-1(2H)-one is a chlorinated dihydronaphthalenone scaffold featuring two chlorine substituents at the 6 and 7 positions. This electron-deficient ring system offers enhanced stability and reactivity for use in transition-metal-catalyzed coupling reactions. The carbonyl group at position 1 enables direct functionalization, while the fused bicyclic core provides rigidity ideal for molecular scaffold design in medicinal chemistry and synthetic intermediates.
6,7-Dichloro-3,4-dihydronaphthalen-1(2H)-one serves as a versatile building block in medicinal chemistry, enabling the synthesis of polycyclic scaffolds through standard electrophilic substitution and transition-metal-catalyzed coupling reactions. Its fused ring system offers enhanced metabolic stability and defined spatial orientation, while the ketone functionality facilitates downstream functionalization via nucleophilic addition or enolization. Bench-stable and compatible with common protecting group strategies, it functions effectively in multi-step syntheses requiring structural rigidity and predictable reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: