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Structure of 2512-24-5
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N-(tert-Butyl)benzenesulfonamide is a bench-stable sulfonamide featuring a sterically hindered tert-butyl group that enhances resistance to nucleophilic attack. This substitution pattern improves metabolic stability and solubility in organic media, making it a robust scaffold for medicinal chemistry. The para-substituted benzene ring provides a rigid platform for molecular integration.
N-(tert-Butyl)benzenesulfonamide serves as a stable, bench-ready sulfonamide building block for medicinal chemistry and synthetic applications. Its tert-butyl group enhances steric protection and improves solubility, facilitating purification and handling. It functions effectively in nucleophilic displacement reactions, enabling the construction of diverse sulfonamide-containing scaffolds relevant to pharmaceutical development. The compound exhibits excellent functional group tolerance and compatibility with standard coupling protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: