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Structure of 2516-95-2
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5-Chloro-2-nitrobenzoic acid features a chlorine atom at the 5-position and a nitro group at the 2-position, creating a strongly electron-deficient aromatic core. This configuration enhances reactivity in electrophilic substitution and facilitates coupling reactions. The carboxylic acid moiety enables direct derivatization or salt formation. Bench-stable and moisture-tolerant, it serves as a key building block for pharmaceutical intermediates and specialty dyes.
5-Chloro-2-nitrobenzoic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct functionalization at the aromatic ring through nucleophilic substitution or transition-metal-catalyzed coupling. The carboxylic acid group facilitates derivatization via esterification, amide formation, or activation for further transformations. Its ortho-nitro and meta-chloro substituents provide predictable reactivity patterns and enhance electrophilic character, supporting efficient heterocycle construction and scaffold diversification under standard bench conditions.
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GHS Pictogram :
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GHS No : GHS05,GHS07,GHS09
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Signal Word : Danger
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UN#: 3077
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Class : 9
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335-H410
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Precautionary Statements : P261-P264-P270-P271-P273-P280-P302+P352-P304+P340-P330-P362+P364-P391-P405-P501
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Lot numbers can be found on the outside label of a product: