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Structure of 252061-66-8
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5-Hydroxyisoindolin-1-one offers a rigid, electron-rich scaffold ideal for constructing bioactive heterocycles. The hydroxyl group enables direct functionalization or hydrogen bonding interactions, while the lactam carbonyl provides polarity and structural stability under standard conditions. This compound serves as a key intermediate in medicinal chemistry campaigns targeting CNS modulators and kinase inhibitors.
5-Hydroxyisoindolin-1-one serves as a versatile scaffold for medicinal chemistry and synthetic organic applications, enabling efficient access to bioactive heterocycles. The hydroxyl group provides a site for derivatization via esterification or ether formation, while the lactam functionality offers hydrogen bonding capacity and structural rigidity. Bench-stable and compatible with standard functional group manipulations, it facilitates diverse transformations in peptide-like molecule synthesis and drug discovery workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: