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Structure of 252288-04-3
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This bench-stable phosphine features a rigid, electron-rich dioxaphosphepin core with stereodefined (11bS) configuration, enabling predictable reactivity in cross-coupling and catalytic transformations. The N,N-diethyl substitution enhances solubility and reduces oxidation susceptibility, while the fused naphthalene framework imparts thermal resilience and steric protection around the phosphorus center.
(11bS)-N,N-Diethyl-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine serves as a chiral phosphine ligand enabling efficient transition-metal-catalyzed cross-coupling reactions. Its rigid, polycyclic framework imparts high thermal stability and robust functional group tolerance, facilitating reproducible coupling outcomes in palladium-catalyzed transformations. The diethylamino group enhances electron density at phosphorus, improving reactivity in Suzuki-Miyaura and Negishi protocols while maintaining ease of purification and handling under standard laboratory conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: