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CS-W001157 4
Total: USD 88.00

(3R,4R)-1-benzyl-4-(hydroxymethyl)pyrrolidin-3-ol

  • CAS No. 253129-03-2

  • Cat. No. CS-0495657
  • Purity≥98%
  • MDL No.MFCD10567193

*For research and further manufacturing use only, not for direct human use.

(3R,4R)-1-benzyl-4-(hydroxymethyl)pyrrolidin-3-ol|CS-0495657

Structure of 253129-03-2

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General Information

  • CAS No. 253129-03-2
  • Cat. No. CS-0495657
  • Purity ≥98%
  • MDL No. MFCD10567193
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₇NO₂
  • Molecular Weight 207.27
  • Synonym(s) (3R,4R)-1-Benzyl-4-hydroxy-3-pyrrolidinemethanol
  • SMILES OC[C@H]1CN(CC2=CC=CC=C2)C[C@@H]1O

Synthesis

  • Route1
    • null|null
      849935-77-9
    • ~75%
    • (3R,4R)-1-benzyl-4-(hydroxymethyl)pyrrolidin-3-ol|CS-0495657
      253129-03-2

    References

    • INDUSTRIAL RESEARCH LIMITED Patent: WO2005/33076 A1, 2005 ; Location in patent: Page/Page column 14; 22 ;
  • Route2
    • null|null
      100-39-0
    • (3R,4R)-4-(Hydroxymethyl)pyrrolidin-3-ol|CS-0496161
      267421-93-2
    • ~%
    • (3R,4R)-1-benzyl-4-(hydroxymethyl)pyrrolidin-3-ol|CS-0495657
      253129-03-2

    References

    • EP1486500 A1, ; Page 15 ;
  • Route3
    • null|null
      100-52-7
    • (3R,4R)-4-(Hydroxymethyl)pyrrolidin-3-ol|CS-0496161
      267421-93-2
    • ~%
    • (3R,4R)-1-benzyl-4-(hydroxymethyl)pyrrolidin-3-ol|CS-0495657
      253129-03-2

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 17 p. 4969 - 4972

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   43.7
  • LogP   0.4716
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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