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Structure of 253677-29-1
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5-Chloro-2-((tert-butoxycarbonyl)amino)benzoic acid features a sterically shielded tert-butyl carbamate group that stabilizes the amine functionality under standard bench conditions. This protected aniline derivative integrates seamlessly into peptide synthesis workflows, enabling selective coupling reactions without side protection. The electron-withdrawing chlorine substituent enhances reactivity at the adjacent carboxylic acid site.
5-Chloro-2-((tert-butoxycarbonyl)amino)benzoic acid serves as a versatile building block for the synthesis of bioactive heterocycles and peptide-conjugated scaffolds. The ortho-chloro and Boc-protected amine functionalities enable sequential functionalization, including palladium-catalyzed coupling reactions and selective deprotection. Its bench-stable nature and compatibility with standard purification methods facilitate efficient integration into multi-step synthetic sequences for medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: