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Structure of 25369-43-1
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2-Oxoindoline-7-carboxylic acid features a fused indoline core with a ketone at the 2-position and a carboxylic acid at the 7-position, enabling direct integration into bioactive molecule scaffolds. This electron-deficient heterocycle supports diverse synthetic transformations under mild conditions, offering high stability and compatibility with standard peptide coupling protocols.
2-Oxoindoline-7-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling efficient construction of indoline-based heterocycles. Its ortho-ketone and carboxylic acid functionalities support diverse transformations, including reductive amination, amide coupling, and cyclization reactions. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis campaigns targeting kinase inhibitors and CNS-active scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: