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Structure of 253787-45-0
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Methyl 8-bromoquinoline-5-carboxylate is a brominated quinoline derivative featuring a methyl ester group at the C5 position. This compound serves as a key intermediate in the synthesis of bioactive heterocycles, leveraging its electron-deficient quinoline core and reactive bromine site for cross-coupling transformations.
Methyl 8-bromoquinoline-5-carboxylate serves as a versatile building block in medicinal chemistry and heterocyclic synthesis. The bromine at the 8-position enables efficient palladium-catalyzed cross-coupling reactions, while the quinoline core provides a rigid, electron-deficient scaffold suitable for bioactive molecule design. The methyl ester group offers a handle for selective reduction or hydrolysis, facilitating downstream functionalization. This compound exhibits excellent bench stability and is compatible with standard synthetic workflows, enabling reliable access to complex quinoline-based architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: