1,5-Naphthyridine

Name: 1,5-Naphthyridine
Brand: ChemScene
Availability: InStock
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CAS No. 254-79-5
Cat. No. CS-B0780
Purity≥98%
MDL No.MFCD00039727

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

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Structure of 254-79-5

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Description

1,5-Naphthyridine is a nitrogen-rich heterocycle featuring two pyridine-like rings fused at the 1,5-positions, offering strong basicity and enhanced π-electron delocalization. This structural motif enables robust coordination in metal complexes and serves as a key scaffold in organic semiconductors and catalytic ligands.

Application

1,5-Naphthyridine serves as a versatile heterocyclic building block in medicinal chemistry and catalysis, offering a rigid, planar scaffold with two nitrogen atoms positioned for orthogonal coordination. It functions as a key structural motif in kinase inhibitors and ligands for transition metal complexes, enabling efficient synthesis of bioactive molecules through standard cross-coupling and electrophilic substitution reactions. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for high-throughput screening and process-scale applications.

General Information

CAS No. 254-79-5
Cat. No. CS-B0780
Purity ≥98%
MDL No. MFCD00039727
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₆N₂
Molecular Weight 130.15
Synonym(s) Pyrido[1,5-b]pyridine
SMILES C12=NC=CC=C1N=CC=C2

Computational Chemistry Data

TPSA 25.78
LogP 1.6298
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05,GHS07
Signal Word : Danger	UN#: 1759
Class : 8	Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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1,5-Naphthyridine

CAS No. 254-79-5

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