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*For research and further manufacturing use only, not for direct human use.
Structure of 254454-54-1
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1-Boc-3-iodoazetidine is a bench-stable, moisture-tolerant azetidine derivative featuring a Boc-protected nitrogen and a reactive iodide at the adjacent carbon. This combination enables direct functionalization in late-stage diversification, particularly in palladium-catalyzed cross-coupling reactions. The strained three-membered ring imparts high reactivity, while the Boc group ensures compatibility with standard synthetic workflows.
1-Boc-3-iodoazetidine serves as a versatile, bench-stable building block for the construction of bioactive azetidine-containing scaffolds. The Boc group provides orthogonal protection for nitrogen functionality, enabling selective deprotection and downstream functionalization. The iodine moiety facilitates efficient palladium-catalyzed cross-coupling reactions, including Suzuki, Stille, and Negishi couplings, allowing rapid diversification in medicinal chemistry and process development workflows. Its stability under standard handling conditions and compatibility with common synthetic protocols make it ideal for modular synthesis of complex heterocyclic systems.
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GHS Pictogram :
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GHS No : GHS07,GHS09
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Signal Word : Warning
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UN#: 3082
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Class : 9
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: