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Structure of 254746-40-2
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Methyl 4-bromo-3-(hydroxymethyl)benzoate features a brominated aromatic ring with a pendant hydroxymethyl group and ester functionality, enabling direct integration into Suzuki-Miyaura couplings and functional group interconversions. This bench-stable compound serves as a versatile synthon for bioactive molecule synthesis.
Methyl 4-bromo-3-(hydroxymethyl)benzoate serves as a versatile building block for transition-metal-catalyzed cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. The bromide functions as a reliable coupling handle in Pd-catalyzed protocols, while the hydroxymethyl group offers orthogonal reactivity for derivatization or protection. Bench-stable and readily purified by silica gel chromatography, it facilitates streamlined synthesis of complex aromatic architectures in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: