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Phenyl(piperidin-4-yl)methanone hydrochloride

  • CAS No. 25519-80-6

  • Cat. No. CS-0112314
  • Purity≥98%
  • MDL No.MFCD00066982

*For research and further manufacturing use only, not for direct human use.

Phenyl(piperidin-4-yl)methanone hydrochloride|CS-0112314

Structure of 25519-80-6

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General Information

  • CAS No. 25519-80-6
  • Cat. No. CS-0112314
  • Purity ≥98%
  • MDL No. MFCD00066982
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₆ClNO
  • Molecular Weight 225.71
  • Synonym(s) 4-Benzoylpiperidine hydrochloride
  • SMILES O=C(C1=CC=CC=C1)C2CCNCC2.[H]Cl

Description

Phenyl(piperidin-4-yl)methanone hydrochloride features a rigid, electron-deficient aryl ketone linked to a sterically hindered piperidine moiety, enabling efficient integration into medicinal chemistry scaffolds. This bench-stable derivative delivers enhanced solubility and metabolic stability in synthetic workflows.

Synthesis

  • Route1

    References

    • TAKEDA PHARMACEUTICAL COMPANY LIMITED Patent: WO2008/11130 A2, 2008 ; Location in patent: Page/Page column 147 ; WO 2008/011130 A2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.1
  • LogP   2.2907
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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